Christopher R.
Butson, PhD
Medical College
of Wisconsin
Title
Evidence-based medicine and clinical decision making in deep brain stimulation
Abstract
Deep brain stimulation (DBS) is a promising approach for several conditions,
especially when alternate treatments have limited efficacy or undesirable side
effects. However, outcomes from DBS are known to be acutely sensitive to the
location and type of stimulation. In addition, physicians have few tools at
their disposal to understand where and how individual patients are stimulated,
or how each patient compares to other in a cohort. We have recently shown that
the use of interactive visualization in clinical decision making for DBS can
provide comparable benefit to standard care but in much less time. We are now
expanding these studies to determine whether this approach can provide improved
symptomatic relief and reduced side effects compared to standard care. To
achieve this goal we must address several distinct problems. First, we
introduce a new type of evidence that combines clinical observation with
computational models. Second, we are integrating this evidence into an
interactive system that runs on mobile computing devices. Third, we are
integrating this system into a clinical workflow for the treatment of
Parkinson's disease patients. In this talk I will present our recent
results and future challenges on this project.
Short bio
Dr. Butson received a B.S. in Mechanical
Engineering from the University of Maryland, M.S. in Electrical Engineering
from George Washington University and Ph.D. in Biomedical Engineering from the
University of Utah. He completed post-doctoral
training at the Cleveland Clinic and is now an Associate Professor at the
Medical College of Wisconsin (MCW) in the Departments of Neurology &
Neurosurgery, and an Adjunct Professor at Marquette University in the
Department of Biomedical Engineering. He
is an active member of the Society for Neuroscience (SFN), the Institute of
Electrical & Electronics Engineers (IEEE) and the Engineering in Medicine & Biology
Society (EMBS). He is President of the Faculty Information Technology Committee
at MCW. He leads a research laboratory which focuses on neuromodulation,
specifically therapeutic and diagnostic brain stimulation.
